2026 Volume 10

Non-Invasive Management of Keloid Scars: Methyl Salicylate Topical
Application and Vitamin D3 Supplementation

Guinevere I. Perry, PhD
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The Combination of Tunnel shaped excision with Radiotherapy and Injection of Type A Botulinum Toxin in the Treatment of Auricular Keloids

Junjie Hou, Chang Liu
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Preclinical Evaluation of Rho-Associated Protein Kinase Inhibitors in Keloid Disease Using 2D, 3D, and Ex Vivo Models

Zeinab Ghasemishahrestani, Traci A. Wilgus, Nonhlanhla P. Khumalo, Ardeshir Bayat
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Real‑world effectiveness and safety of bleomycin in patients with keloids and hypertrophic scars: a systematic review and meta‑analysis

Qimeng Wang, Zhesheng Ren, Wenyu Jin, Zhehu Jin
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Four-Color Aesthetic Evaluation for Auricular Keloids: A Pragmatic Tool for Contour, Visibility, and Follow-up Communication

Xiao-Mei Han, Co-authors: Shao-Qian Jiang; Cai-Xia Hu; Ming Du
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Transcriptional Profiles of Keloid Tissue and Matched Normal Skin Tissue Reveal Heterogeneity in Fibroblast Subtype Enrichment, Gene Expression, and Immune Cell Responses

Jonathan J. Panzer, Mingming Pan, Mrudula Nair, Ian M. Loveless, Indra Adrianto, Ling Huang, Dhananjay Chitale, Christina de Guzman Strong, Albert M. Levin, Lamont R. Jones
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Atypical Post-Surgical Keloid-Like Scar of the Nasal Tip Mimicking Cutaneous Sarcoidosis

Charvet E1, Battistella M2, Cassius C1, Ferrero L1, Jachiet M1, Bouaziz J-D1, El Lakkiss S1
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Standard keloid surgical treatment at our department: Couse of treatment and the result

Mika ikeda MD,PhD, Haruka Matsuzoe MD, Tomoya Kawabata MD, Motoko Naitoh MD,PhD, Kazuya Kataoka MD,PhD
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Epidermal Cysts Associated With Refractory Keloid Lesions: A Three-Case Series

Kwang Sik Seo(MD), CO-AUTHORS: Su Bong Nam(MD-PhD), Jung Yeol Seo(MD
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The Effect of CO2Laser Intervention on Recurrence Prevention After Keloid Ulcer Healing

Xiqiao Wang , Jiarong Yu, Yan Liu
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Integrated Surgical Debulking Combined with Laser and Radiotherapy (SLCR) for Complex Keloids

Xiaoli Wu
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KECORT study: an international e-Delphi study on the treatment of Keloids using intralesional Corticosteroids in clinical practice

Qi Yin (MD), Albert Wolkerstorfer (MD, PhD)
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Effect of Keloid Properties on Treatment Efficacy: A Systematic Review

Vazula Bekkers1 (MD, PhD), Paul Barsom2 (MD), Qi Yin2 (MD, PhD), Frank Niessen3, Paul van Zuijlen3-6 (MD, PhD), Oren Lapid3-5 (MD, PhD), Martijn van Doorn (MD, PhD)1, Albert Wolkerstorfer2 (MD, PhD)
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Treatment of Mandibular Keloids Using the Micro-Trephine Punch Technique, Alone or with Excision, Followed by Radiotherapy

Jian Zhong Peng, MD, Xian Yan Luo, MD
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The Combination of the Mini-punch Technique and Photodynamic Therapy for the Treatment of Mandibular Keloids and Hypertrophic Scars

Xian Yan Luo, MD , Jian Zhong Peng, MD
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A Combined Protocol for Toe Keloid Lesions After Pediatric Syndactyly Release

Liu Xurong, Renliang He
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Multi-antigen Imaging Reveals Inflammatory DC, Adam17 And Neprilysin As Effectors In Keloid Formation

Jürgen Bauerschmitz 3 4 5 Mathias Rath 1, Alain Pitiot 2, Michael Kirr 3 4 5, Waltraud Fröhlich 3 4 5, Bianca Plosnita 6, Stefan Schliep 3 4 5, , Andreas S Baur 3 4 5, Christian Ostalecki 3
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Comparison of Quantitative Evaluation and Conventional Scar Scale Analysis for Pediatric Pathological Scars

Jin-Ye Guan 1,†, Xing Zou 1,†, Jun-Wen Ge 1 , Rui-Cheng Tian 1, Wei Liu 2 , Mei-Yun Li 1,* and Dan Deng 1,*
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Multimodal Management of Keloids in Dark Skin: Clinical Experience from Agadir, Morocco

Ilham Oulhous, MD
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Exploring the mechanisms of keloid recurrence

Rozan Odeh Alkresheh, Wolfgang Jarolimek, Ross Hamilton, Fiona Wood, K. Swaminathan Iyer, Nicole M. Smith, Lucy W. Barrett, Andrew Stevenson, Mark W. Fear
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Psychosocial Impact of Keloid Disorder: A Comparative Study of Body App reciation, Anxiety, and Depression against Hypertrophic and Post-Burn Scars

Sofia de Carvalho Leal, MS1, Débora Barbosa Rocha Ribas, MS2, Maria Eduarda Barbieri Orta, MS3, Luciana Nacif da Costa Valle, MD4, Gisele Viana de Oliveira, PhD5
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The SCAR WARS project: a pilot study evaluating the effectiveness and safety of a compressive device intended to prevent recurrence of keloid scars after surgical resection

Thomas Lihoreau1,2, Brice Chatelain3 , Aurélien Louvrier1,3, Christophe Meyer1,3, Lionel Pazart1,2,4, Guillaume Besch1,2,5, Gwenaël Rolin1,6
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Inflammatory Keloid Fibroblasts Promote CCL2-Dependent Monocyte Recruitment and Polarization Toward M2-like Macrophages

Yasmin El MAHI1, Hanane QABALI1, Thomas LIHOREAU2, Brice CHATELAIN3, Céline VIENNET1,4, Francis BONNEFOY1, Gwenaël ROLIN1,4,5
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Clinical Efficacy of the ASAP Algorithm: A prospective cohort study of 354 keloids in 280 patients

Débora Barbosa Rocha Ribas, MS1, Maria Eduarda Barbieri Orta, MS2, Sofia de Carvalho Leal, MS3, Luciana Nacif da Costa Valle, MD4, Gisele Viana de Oliveira, PhD5
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Impact of the A.S.A.P. Protocol on Quality of Life and Depression in Keloid Disorder: A Pre–Post Longitudinal Study

Maria Eduarda Barbieri Orta, MS1 , Sofia de Carvalho Leal, MS2 , Débora Barbosa Rocha Ribas, MS3, Luciana Nacif da Costa Valle, MD4 ,Gisele Viana de Oliveira, PhD5
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The Implications of 3D Culture Models on Keloid Research: A Systematic Review

Trecy Hemedi
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Innovative Treatment Modalities for Keloids: Contact Cryotherapy

Michael H Tirgan MD
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Challenges in the Treatment of Pediatric Keloids

Michael H Tirgan MD
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Cartesian Model of Clinical Behavior of Keloid Disorder, Implementation and Update of the Keloid Staging System and Call for Establishment of International

Michael H Tirgan MD
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The Evolving Role of Radiotherapy in Keloid Management, Optimisation of BED Values and Fractionation Regimens: A 30-Year UK Perspective

Henry Weatherburn1 PhD and John Glees1 MD, FRCR, DMRT and Kamal Malaker2 MD, PhD
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A Comparison of the Characteristics of Megavoltage Electron Beams and Superficial X-Ray Beams Used in Keloid Treatment

Henry Weatherburn PhD and John Glees MD, FRCR, DMRT
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Keloid Treatment by External Beam Radiotherapy – Optimisation of BED Values and Fractionation Regimens

Henry Weatherburn1 PhD and John Glees1 MD, FRCR, DMRT and Kamal Malaker2 MD, PhD
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A Revolutionary New Combined Treatment for Aggressive Keloid Tumours Without Need for Surgery: A Patient Series

John Glees1 MD, FRCR, DMRT, Patricia Yap2 BSc, MBBS, Dip Derm and Henry Weatherburn1 PhD
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Fibroblast Heterogeneity and its Role in Keloid pathogenesis Implication for targeted drug development

Jong Hee Lee, MD, PhD
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Intralesional Treatment Strategies for Keloids: An Operative Principle Centered on the Preservation of Healthy Skin

Xie Chunhui 1, Yu Jiaao 1, Gao Xinxin 1, Wu Xiaoli 2
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Ai-assisted Integrative Transcriptomic Analysis Supports Mechanistic Delineation Of Nodular And Extensive Keloid Subtypes With Therapeutic Implications

Kevin Serror 1,2,3*°, Lina Faik 4°, Thaïs Hennebelle 1,2, Xavier Sécheresse 4 , Léa Nicosia 1,2, Pierre De La Grange 5 , David Boccara 3 , Marc Chaouat 3, Jean-David Bouaziz 1,2,6, Joël Belafa 4 , Maxime Gobin 4 , Antoine De Torcy 4 , Florence Armstrong 4#, and Laurence Michel 1,2,6*#
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Does Vitamin D Signaling Play a Role in Keloid Pathology?

Dorothy M. Supp, PhD1,2; Caitlin Phillips, BS2; Jane Young, BS2 ; Jennifer M. Hahn, BS1 ; Heather M. Powell, PhD3,2; Sara Higginson, MD, FACS2
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Pathophysiology of Pruritus in Keloids: Site-Specific Analysis of Neuro-Immune Interactions

Dorothy M. Supp, PhD1,2; Caitlin Phillips, BS2; Jane Young, BS2; Jennifer M. Hahn, BS1; Heather M. Powell, PhD3,2; Sara Higginson, MD, FACS2 Haruka Matsuzoe1, Mika Ikeda1, Motoko Naitoh1, Tomoya Kawabata1,2, Mizuki Teramoto1, Yoshikuni Suzuki1, Kazuya Kataoka1
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Non-Surgical Management of Earlobe Keloids: A Patient-Centered,Multimodal Approach, Case Study and International Collaboration Experience

Heather M. Powell, PhD3,2; Sara Higginson, MD, FACS2 Raul Caceres, MD1, 2, Michael Tirgan, MD1
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The Use of Topical Treatment to Treat Keloid Scars resulting from Burn Grafts from both Donor and Recipient sites- after failed traditional treatment - A case study.

Patricia Yap, MD
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Comparison Of Punch Excision Combined With Intralesional Triamcinolone Acetonide And 5-fluorouracil Injection Versus Intralesional Triamcinolone Acetonide And 5-fluorouracil Injection Alone For The Treatment Of Keloids: A Single-blinded Randomized Clinical Trial

Peijun Mai1, Xianzhong Zhu1,2, Yurui Han1, Qing Qi
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Adjuvant Radiotherapy for the Treatment of Keloids

Supp, PhD1,2; Caitlin Phillips, BS2; Jane Young, BS2; Jennifer M.
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Pathophysiology of Pruritus in Keloids: Site-Specific Analysis of Neuro-Immune Interactions

Haruka Matsuzoe1, Mika Ikeda1, Motoko Naitoh1, Tomoya Kawabata1,2, Mizuki Teramoto1 , Yoshikuni Suzuki1, Kazuya Kataoka1
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DNA Methylation Drives Osteochondrogenic Reprogramming in Keloid Pathogenesis And Reveals Therapeutic Potential of Decitabine

M. Supp, PhD1,2; Caitlin Phillips, BS2; Jane Young, BS2; Jennifer M. Hahn, BS1; Heather M. Powell, PhD3,2; Sara Higginson, MD, FACS2
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Psychological Assessment of Anxiety and Depression in Patients with Single versus Multiple Keloids: A Cross-Sectional Study

Lian Zhang*, MD, PhD, Yanyu Du*, MD, Dan Sun*, MD, PeiPei Huang, Renliang He#, MD, Bin Yang#, MD
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Are We Using Too Much Triamcinolone Acetonide for Intralesional Keloid Therapy? Correlation between in vitro and in vivo data.

Nina Zamani1, M.Sc., Michael Tirgan2, M.D., Akash Gunjan1*, Ph.D.
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CatecholaminergiC neurons drive fibro-osseous reprogramming of keloid fibroblasts via ADRB1-TSN signaling axis*

Rui Chen
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Basal Cell Carcinoma Secondary to a Chest Keloid: A Case Report and literature review

You Wu1 Youbin Wang MD2
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Time to Change the Paradigm: Keloid Disorder as a Systemic Disease

Youbin Wang MD
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