Abstract
Keloid is a challenging disease boasting a high recurrence rate after various therapies. This situation has remained largely unchanged over the past decades. The most likely reason is that keloid is commonly regarded as a pure skin lesion, and al efforts in mechanistic and therapeutic investigations are solely targeted at keloid tissue/cells. In contrast, traditional Chinese medicine views all diseases as the results of an imbalanced internal environment of individuals or an imbalance between individuals and their external environments. An optimal therapy should involve restoring the balance along with targeted treatment.