Comparison Of Punch Excision Combined With Intralesional Triamcinolone Acetonide And 5-fluorouracil Injection Versus Intralesional Triamcinolone Acetonide And 5-fluorouracil Injection Alone For The Treatment Of Keloids: A Single-blinded Randomized Clinical Trial
Peijun Mai, Xianzhong Zhu, Yurui Han, Qing Qi
BACKGROUND
While some studies have shown the favorable efficacy of punch therapy for keloids, the effectiveness and safety of punch excision combined with intralesional triamcinolone acetonide (TAC) and 5-fluorouracil (5-FU) injection were uncertain. Here, we conducted a randomized controlled clinical trial to investigate the effectiveness and safety of punch excision combined with intralesional triamcinolone acetonide and 5-fluorouracil injection for keloids.
CONCLUSION
Punch excision combined with intralesional TAC and 5-FU injection is a promising therapeutic approach for keloids, achieving enhanced efficacy, minimized long-term adverse effects, and improved quality of life.
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