Cartesian Model of Clinical Behavior of Keloid Disorder, Implementation and Update of the Keloid Staging System and Call for Establishment of International Keloid Registry
Michael H. Tirgan, MD
BACKGROUND
BKeloid disorder (KD) has highly variable clinical behavior. KD ranges from patients who in their lifetime develop one or a few keloid lesions to those who within a few years develop very extensive disease involving various parts of their skin. To the author’s knowledge, this very important aspect of the disorder has never been studied and thus never incorporated into an analysis of clinical or laboratory data from keloid patients.
CONCLUSION AND RELEVANCE
Proper comparison of clinical and/or laboratory outcome data is meaningful only when such a comparison is made among patients with similar biology and clinical behavior. The author recommends that keloid researchers incorporate the variable patterns of clinical behavior of KD in planning clinical or laboratory experiments, as well as in analysis of their data. Call is made for all keloid researchers to collaborate in establishing an international Keloid Registry.
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