Intralesional Treatment Strategies for Keloids: An Operative Principle Centered on the Preservation of Healthy Skin
Xie Chunhui 1, Yu Jiaao 1
BACKGROUND
Keloids are characterized by a significant tendency toward recurrence and are closely associated with individual genetic susceptibility. Clinical observations indicate that even minimal skin trauma can induce persistent keloidal proliferation at the injury site in susceptible individuals. Therefore, in the treatment of keloids, avoiding iatrogenic injury to healthy skin represents a fundamental principle for preventing recurrence. This study aims to investigate therapeutic strategies strictly confined to the boundaries of the original lesion, evaluating their clinical value in preserving healthy skin and controlling recurrence.
CONCLUSION
A therapeutic strategy guided by the preservation of healthy skin and strictly confined to the original lesion boundaries constitutes an essential principle in the
comprehensive management of keloids. By strictly restricting the operative space to the original lesion, this approach prevents iatrogenic damage to healthy skin and
the resultant secondary scar formation, thereby providing both a theoretical basis and a clinical pathway for reducing recurrence rates. Further efforts are warranted to standardize the indications and outcome assessment criteria for various intralesional therapeutic modalities.
The methods, results, figures and the downloadable PDF are available to subscribers.
