Transcriptional Profiles of Keloid Tissue and Matched Normal Skin Tissue Reveal Heterogeneity in Fibroblast Subtype Enrichment, Gene Expression, and Immune Cell Responses

Jonathan J. Panzer, Mingming Pan, Mrudula Nair, Ian M. Loveless, Indra Adrianto, Ling Huang, Dhananjay Chitale, Christina de Guzman Strong, Albert M. Levin, Lamont R. Jones

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Transcriptional Profiles of Keloid Tissue and Matched Normal Skin Tissue Reveal Heterogeneity in Fibroblast Subtype Enrichment, Gene Expression, and Immune Cell Responses

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Jonathan J. Panzer¹, Mingming Pan¹, Mrudula Nair¹, Ian M. Loveless¹, Indra Adrianto¹, Ling Huang², Dhananjay Chitale³, Christina de Guzman Strong⁴, Albert M. Levin¹, Lamont R. Jones⁵

  1. Department of Public Health Sciences,
    Henry Ford Health (HFH), Detroit,
    MI, USA
  2. Henry Ford Pancreatic Cancer Center,
    Department of Surgery, Detroit, MI,
    USA
  3. Department of Pathology, Henry Ford
    Health (HFH), Detroit, MI, USA
  4. Department of Dermatology, Henry
    Ford Health (HFH), Detroit, MI, USA
  5. Henry Ford Medical Group (HFMG),
    Department of Otolaryngology, Detroit,
    MI, USA

Running Title
Transcriptional Profiles of Keloid Tissue
and Matched Normal Skin Tissue Reveal
Heterogeneity in Fibroblast Subtype
Enrichment, Gene Expression, and
Immune Cell Responses


Word Count - 402 words

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